php与apache整合都时候出错

编译完php，修改完httpd.conf，重启apache都时候提示

httpd: Syntax error on line 53 of /usr/local/apache/conf/httpd.conf: Cannot load /usr/local/apache/modules/libphp5.so into server: /usr/local/apache/modules/libphp5.so: cannot restore segment prot after reloc: Permission denied

apache和php重新编译了无数次都是这样，到底哪里出错了

环境是centos5